#4905 PERITONEAL CLEARANCE OF TRACE ELEMENTS IN PERITONEAL DIALYSIS PATIENTS

Abstract Background and Aims Both accumulations deficiencies of trace elements (TE) could be seen in peritoneal dialysis (PD) patients. Peritoneal clearance remains major route elimination for many solutes including TE, PD Imbalances TE may have deleterious effects on the Data balances patients are inadequate. Here, we present some data from a larger study. We aimed to analyze Boron (B), Cupper (Cu), Zinc (Zn), Selenium (Se), Strontium (Sr) Molybdenum (Mo) cohort Method This cross-sectional study included three female five male giving consent Mean age was 43,6±5,6 were continuous ambulatory at least months. Patients with recent peritonitis excluded. solutions individualized, so had different osmolarities. A sample plasma 24-hour spent dialysate analyzed by inductively coupled mass spectrometry (ICP-MS) (Thermo Scientific™ iCAP Q ICP-MS, USA). Sensitivity order ppb (μg/L). control group (CG) glomerular filtration rate ≥ 90 ml/min used comparison levels TE. clearances calculated following formula: ${\fontsize{5}{7}\selectfont{24 \!-\! hour \, spent\, dialysate\, volume \!\times\! \displaystyle\frac{{dialysate\ concentration\ of\ the\ trace\ element}}{{plasma\ element}}}}$ Results levels, daily loss shown Table 1. The ordered smallest largest as follows: Zn, Cu, Se, Sr, Mo, Ni, B. On other hand, element losses highest Cr, B Conclusion Our provides elements, which help better understand balance suggest that has Zn lowest values.